Thrombophilia: the dermatological clinical spectrum

Thrombophilia: the dermatological clinical spectrum

The aim of this article is to review the hypercoagulable states (thrombophilia) most commonly encountered by dermatologists, as well as their cutaneous signs, including livedo racemosa, cutaneous necrosis, digital ischemia and ulcerations, reticulated purpura, leg ulcers, and other skin conditions. Recognizing these cutaneous signs is the first step to proper treatment. Our aim is to describe w...

Clinical aspects of venous thrombophilia.

Venous thrombophilia is the result of clotting changes namely of a hypercoagulable state together with blood flow and vessel wall changes. There is no need for all these components to be present in order for thrombosis to occur. As the matter of fact, thrombosis may occur even if only one of these conditions is present. In clinical practice a combination of factors is usualy seen. In comparison...

Testing for thrombophilia: clinical update.

British Journal of General Practice, February 2014 e120 baCKGROUND Thrombophilia describes inherited and acquired prothrombotic states which predispose to venous, but not arterial thromboembolism. The heritable states are of limited clinical significance in primary care and while they may underlie a patient’s presentation with deep venous thrombosis (DVT) or pulmonary embolism (PE) of uncertain...

Some aspects of dermatological clinical trials.

Inherited thrombophilia: pathogenesis, clinical syndromes, and management.

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